Significance of TNF-α and IL-6 expression in invasive pituitary adenomas.

نویسندگان

  • J L Wu
  • J Y Qiao
  • Q H Duan
چکیده

The aim of this study was to investigate expression of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in invasive pituitary adenomas (IPAs). The streptavidin peroxidase immunohistochemical method was employed to detect their expression in 40 cases of IPA and 40 of non-invasive pituitary adenoma (NIPA). TNF-α and IL-6 were found to be upregulated in IPA tissue compared with that of NIPA (P < 0.05). These proteins may therefore play important roles in the occurrence and progression of IPA.

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عنوان ژورنال:
  • Genetics and molecular research : GMR

دوره 15 1  شماره 

صفحات  -

تاریخ انتشار 2016